Abstract A46: Loss of DOK2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis

Michele Vigliotti; Elena Lum; nilanjana Banerjee; Noelle Cutter; Kazimierz O. Wrzeszczynski; Sohail Khan; Sitharthan Kamalakaran; Douglas A. Levine; Nevenka Dimitrova; Robert Lucito

doi:10.1158/1078-0432.OVCA13-A46

Abstract A46: Loss of DOK2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis

Michele Vigliotti, Elena Lum, nilanjana Banerjee, Noelle Cutter, Kazimierz O. Wrzeszczynski, Sohail Khan, Sitharthan Kamalakaran, Douglas A. Levine, Nevenka Dimitrova, Robert Lucito

Biology, Chemistry, Environmental Studies

Research & Scholarship: Contribution to conference › Abstract

Original language	American English
DOIs	https://doi.org/10.1158/1078-0432.OVCA13-A46
State	Published - Oct 1 2013

Disciplines

Biology
Oncology
Immunology and Infectious Disease

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10.1158/1078-0432.OVCA13-A46License: Unspecified

Cite this

@conference{d9ecdda9f9b343d6bd83d9368aaa9ae9,

title = "Abstract A46: Loss of DOK2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis",

author = "Michele Vigliotti and Elena Lum and nilanjana Banerjee and Noelle Cutter and Wrzeszczynski, \{Kazimierz O.\} and Sohail Khan and Sitharthan Kamalakaran and Levine, \{Douglas A.\} and Nevenka Dimitrova and Robert Lucito",

note = "Ovarian cancers are highly heterogeneous and while chemotherapy is the preferred treatment many patients are intrinsically resistant or quickly develop resistance. Furthermore, all tumors that recur ultimately become resistant. Recent evidence suggests that epigenetic deregulation may be a key factor in the onset and maintenance of chemoresistance.",

year = "2013",

month = oct,

day = "1",

doi = "10.1158/1078-0432.OVCA13-A46",

language = "American English",

}

TY - CONF

T1 - Abstract A46: Loss of DOK2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis

AU - Vigliotti, Michele

AU - Lum, Elena

AU - Banerjee, nilanjana

AU - Cutter, Noelle

AU - Wrzeszczynski, Kazimierz O.

AU - Khan, Sohail

AU - Kamalakaran, Sitharthan

AU - Levine, Douglas A.

AU - Dimitrova, Nevenka

AU - Lucito, Robert

N1 - Ovarian cancers are highly heterogeneous and while chemotherapy is the preferred treatment many patients are intrinsically resistant or quickly develop resistance. Furthermore, all tumors that recur ultimately become resistant. Recent evidence suggests that epigenetic deregulation may be a key factor in the onset and maintenance of chemoresistance.

PY - 2013/10/1

Y1 - 2013/10/1

U2 - 10.1158/1078-0432.OVCA13-A46

DO - 10.1158/1078-0432.OVCA13-A46

M3 - Abstract

ER -