Adding Oral Alisertib to Weekly Paclitaxel for Metastatic Breast Cancer

Research & Scholarship: Non-textual formWeb publication/site

Abstract

A randomized phase II trial investigated the effect of adding the Aurora kinase A inhibitor alisertib to a reduced dose of weekly paclitaxel in the treatment of patients with estrogen receptor–positive, ERBB2-negative, or triple-negative metastatic breast cancer. According to Joyce O’Shaughnessy, MD, and researchers from Baylor University Medical Center, Dallas, the combination treatment significantly improved progression-free survival compared with paclitaxel alone. Their findings were published in JAMA Network Open.
Original languageAmerican English
StatePublished - May 26 2021

Disciplines

  • Life Sciences
  • Medicine and Health Sciences

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