Adjuvant Treatment of Early-Stage Breast Cancer: T-DM1 Versus Paclitaxel Plus Trastuzumab

Research & Scholarship: Non-textual formWeb publication/site

Abstract

Adjuvant paclitaxel with trastuzumab is a common combination treatment for invasive early breast cancers with overexpression of HER2. In a phase II clinical trial, Sara M. Tolaney, MD, MPH, and colleagues from the Dana-Farber Cancer Institute, Boston, reported that 1 year of adjuvant therapy with trastuzumab emtansine (T-DM1) resulted in “excellent” invasive disease–free survival compared with paclitaxel plus trastuzumab but not a real difference in clinically relevant toxicities. Their results were reported in the Journal of Clinical Oncology.
Original languageAmerican English
StatePublished - Sep 7 2021

Disciplines

  • Life Sciences
  • Medicine and Health Sciences

Cite this