Next-Generation Sequencing in AML: Case Report Focuses on NUP214-ABL1 Gene Fusion

Description

The tyrosine kinase fusion gene NUP214-ABL1 has been detected in both patients with T-cell acute lymphoblastic leukemia and B-cell acute lymphoblastic leukemia. Recently, Huan-Ping Wang, MD, and colleagues from Zhejiang University, Hangzhou, China, shared the case details of what they believe may be the first patient with acute myeloid leukemia (AML) harboring the NUP214-ABL1 gene fusion, who was treated successfully with conventional chemotherapy. The report was published in Frontiers in Oncology.