!!Research output per year
!!Research output per year
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About
Investigations of the function and signaling pathways of the endogenous opioid system, with a focus on novel ligands of the kappa opioid receptor. Potential implications of novel kappa opioid agonists, antagonists, and partial agonists include new pharmacotherapeutics for the treatment of cocaine and methamphetamine use disorders, pain states, pruritis, depression, and multiple sclerosis, among others.
Disciplines
- Biochemistry, Biophysics, and Structural Biology
- Neuroscience and Neurobiology
- Pharmacology, Toxicology and Environmental Health
- Research Methods in Life Sciences
- Chemicals and Drugs
- Chemistry
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Addictions
Reed, B., Butelman, E. R., Yuferov, V. & Kreek, M. J., ene 1 2023, Neurobiology of Brain Disorders.Producción científica: Chapter
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The Kappa Opioid Receptor: Candidate Pharmacotherapeutic Target for Multiple Sclerosis
Reed, B. & Dutta, S., ene 1 2023, En: Drugs and Drugs Candidates. 2, 4Producción científica: Article › revisión exhaustiva
Acceso abierto -
Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel Kappa Opioid Receptor Agonist Scaffold
Reed, B., Miller, M., Michino, M., Butelman, E. R., Ben-Ezra, A., Pikus, P., Morochnik, M., Kim, Y., Ripka, A., Vacca, J. & Kreek, M. J., jul 1 2022, En: ACS Chemical Neuroscience. 13, 13Producción científica: Article › revisión exhaustiva
Acceso abierto -
Kappa Opioid Receptor Antagonists as Potential Therapeutics for Mood and Substance Use Disorders
Reed, B., Butelman, E. R. & Kreek, M. J., 2022, En: Handbook of Experimental Pharmacology. 271Producción científica: Article › revisión exhaustiva
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Genetic Vulnerability to Opioid Addiction
Reed, B. & Kreek, M. J., 2021, En: Cold Spring Harbor Perspectives in Medicine. 11Producción científica: Article › revisión exhaustiva
Prensa/Medios de comunicación
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US Patent Issued to The Rockefeller University on Aug. 17 for "Pyrano[3,4-bpyrazine kappa opioid receptor ligands for treating addiction, pruritus, pain, and inflammation" (New York, Massachusetts Inventors)
8/18/21
1 elemento de Cobertura del medio de comunicación
Prensa/medios de comunicación: Research