Enhanced tumor formation in mice heterozygous for Blm mutation

Kathleen Heppner Goss; Mary A. Risinger; Jennifer J. Kordich; Maureen M. Sanz; Joel E. Straughen; Lisa E. Slovek; Anthony J. Capobianco; James German; Gregory P. Boivin; Joanna Groden

doi:10.1126/science.1074340

Enhanced tumor formation in mice heterozygous for Blm mutation

Kathleen Heppner Goss
, Mary A. Risinger
, Jennifer J. Kordich
, Maureen M. Sanz
, Joel E. Straughen
, Lisa E. Slovek
, Anthony J. Capobianco
, James German
, Gregory P. Boivin
, Joanna Groden

Biology, Chemistry, Environmental Studies

University of Cincinnati

Producción científica: Article › revisión exhaustiva

Idioma original	American English
Publicación	Science
Volumen	297
DOI	https://doi.org/10.1126/science.1074340
Estado	Published - sept 20 2002

Disciplines

Genetics
Biology
Oncology

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10.1126/science.1074340

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@article{daf442a30b18469d87f33886872642ac,

title = "Enhanced tumor formation in mice heterozygous for Blm mutation",

author = "Goss, \{Kathleen Heppner\} and Risinger, \{Mary A.\} and Kordich, \{Jennifer J.\} and Sanz, \{Maureen M.\} and Straughen, \{Joel E.\} and Slovek, \{Lisa E.\} and Capobianco, \{Anthony J.\} and James German and Boivin, \{Gregory P.\} and Joanna Groden",

note = "Persons with the autosomal recessive disorder Bloom syndrome are predisposed to cancers of many types due to loss-of-function mutations in the BLM gene, which encodes a recQ-like helicase.",

year = "2002",

month = sep,

day = "20",

doi = "10.1126/science.1074340",

language = "American English",

volume = "297",

journal = "Science",

publisher = "American Association for the Advancement of Science (AAAS)",

}

TY - JOUR

T1 - Enhanced tumor formation in mice heterozygous for Blm mutation

AU - Goss, Kathleen Heppner

AU - Risinger, Mary A.

AU - Kordich, Jennifer J.

AU - Sanz, Maureen M.

AU - Straughen, Joel E.

AU - Slovek, Lisa E.

AU - Capobianco, Anthony J.

AU - German, James

AU - Boivin, Gregory P.

AU - Groden, Joanna

N1 - Persons with the autosomal recessive disorder Bloom syndrome are predisposed to cancers of many types due to loss-of-function mutations in the BLM gene, which encodes a recQ-like helicase.

PY - 2002/9/20

Y1 - 2002/9/20

U2 - 10.1126/science.1074340

DO - 10.1126/science.1074340

M3 - Article

VL - 297

JO - Science

JF - Science

ER -