Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.

Alex S. Nord; Wendy Roeb; Diane E. Dickel; Tom Walsh; Mary Kusenda; Kristen Lewis O'Connor; Dheeraj Malhotra; Shane E. McCarthy; Sunday M. Stray; Susan M. Taylor; Jonathan Sebat; Bryan King; Mary Claire King; Jon M. McClellan

doi:10.1038/ejhg.2011.24

Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.

Alex S. Nord
, Wendy Roeb
, Diane E. Dickel
, Tom Walsh
, Mary Kusenda
, Kristen Lewis O'Connor
, Dheeraj Malhotra
, Shane E. McCarthy
, Sunday M. Stray
, Susan M. Taylor
, Jonathan Sebat
, Bryan King
, Mary Claire King
, Jon M. McClellan

Biology, Chemistry, Environmental Studies

University of Washington
Lawrence Berkeley National Laboratory
Stony Brook University
National Institute of Standards and Technology
University of California, San Diego
Cold Spring Harbor Laboratory

Producción científica: Article › revisión exhaustiva

Idioma original	American English
Publicación	European Journal of Human Genetics
Volumen	19
DOI	https://doi.org/10.1038/ejhg.2011.24
Estado	Published - jun 1 2011

Disciplines

Biology
Bioinformatics
Genetics

Acceder al documento

10.1038/ejhg.2011.24

Citar esto

@article{07f80fb40f8749f18a6f9de68a7b87cf,

title = "Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.",

author = "Nord, \{Alex S.\} and Wendy Roeb and Dickel, \{Diane E.\} and Tom Walsh and Mary Kusenda and O'Connor, \{Kristen Lewis\} and Dheeraj Malhotra and McCarthy, \{Shane E.\} and Stray, \{Sunday M.\} and Taylor, \{Susan M.\} and Jonathan Sebat and Bryan King and King, \{Mary Claire\} and McClellan, \{Jon M.\}",

note = "Individuals with autism are more likely to carry rare inherited and de novo copy number variants (CNVs). However, further research is needed to establish which CNVs are causal and the mechanisms by which these CNVs influence autism. We examined genomic DNA of children with autism (N=41) and healthy controls (N=367) for rare CNVs using a high-resolution array comparative genomic hybridization platform.",

year = "2011",

month = jun,

day = "1",

doi = "10.1038/ejhg.2011.24",

language = "American English",

volume = "19",

journal = "European Journal of Human Genetics",

issn = "1476-5438",

publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.

AU - Nord, Alex S.

AU - Roeb, Wendy

AU - Dickel, Diane E.

AU - Walsh, Tom

AU - Kusenda, Mary

AU - O'Connor, Kristen Lewis

AU - Malhotra, Dheeraj

AU - McCarthy, Shane E.

AU - Stray, Sunday M.

AU - Taylor, Susan M.

AU - Sebat, Jonathan

AU - King, Bryan

AU - King, Mary Claire

AU - McClellan, Jon M.

N1 - Individuals with autism are more likely to carry rare inherited and de novo copy number variants (CNVs). However, further research is needed to establish which CNVs are causal and the mechanisms by which these CNVs influence autism. We examined genomic DNA of children with autism (N=41) and healthy controls (N=367) for rare CNVs using a high-resolution array comparative genomic hybridization platform.

PY - 2011/6/1

Y1 - 2011/6/1

U2 - 10.1038/ejhg.2011.24

DO - 10.1038/ejhg.2011.24

M3 - Article

SN - 1476-5438

VL - 19

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

ER -